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cpg odn 2395  (InvivoGen)


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    InvivoGen cpg odn 2395
    Cpg Odn 2395, supplied by InvivoGen, used in various techniques. Bioz Stars score: 96/100, based on 414 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cpg odn 2395/product/InvivoGen
    Average 96 stars, based on 414 article reviews
    cpg odn 2395 - by Bioz Stars, 2026-06
    96/100 stars

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    Frequency of tonsillar pDCs positively correlates with the expression of mRNAs encoding APRIL, BAFF and TLR9 in tonsillar MNCs from patients with IgAN. Correlation analysis was performed between the frequency of tonsillar pDCs and gene expression in tonsillar MNCs from patients with IgAN ( n = 10, red dots) and CT ( n = 9, black dots). ( A ) Correlation between the percentage of tonsillar pDCs and the expression of TLR9 in tonsillar MNCs from patients with IgAN and CT. ( B ) Correlation between the percentage of tonsillar pDCs and the expression of IL-6 in tonsillar MNCs from patients with IgAN and CT. ( C ) Correlation between the percentage of tonsillar pDCs and the expression of BAFF in tonsillar MNCs from patients with IgAN and CT. ( D ) Correlation between the percentage of tonsillar pDCs and the expression of APRIL in tonsillar MNCs from patients with IgAN and CT. Spearman’s correlation coefficients (r) and P -values are shown in each panel. * P ≤ .05.

    Journal: Nephrology Dialysis Transplantation

    Article Title: Plasmacytoid dendritic cells modulate the production of mucosal IgA in IgA nephropathy

    doi: 10.1093/ndt/gfaf216

    Figure Lengend Snippet: Frequency of tonsillar pDCs positively correlates with the expression of mRNAs encoding APRIL, BAFF and TLR9 in tonsillar MNCs from patients with IgAN. Correlation analysis was performed between the frequency of tonsillar pDCs and gene expression in tonsillar MNCs from patients with IgAN ( n = 10, red dots) and CT ( n = 9, black dots). ( A ) Correlation between the percentage of tonsillar pDCs and the expression of TLR9 in tonsillar MNCs from patients with IgAN and CT. ( B ) Correlation between the percentage of tonsillar pDCs and the expression of IL-6 in tonsillar MNCs from patients with IgAN and CT. ( C ) Correlation between the percentage of tonsillar pDCs and the expression of BAFF in tonsillar MNCs from patients with IgAN and CT. ( D ) Correlation between the percentage of tonsillar pDCs and the expression of APRIL in tonsillar MNCs from patients with IgAN and CT. Spearman’s correlation coefficients (r) and P -values are shown in each panel. * P ≤ .05.

    Article Snippet: The TLR9 agonist class C CpG-ODN (ODN 2395, InvivoGen), which stimulates pDCs and B cells [ ], was intranasally administered to each group of mice every 2 days for 3 weeks.

    Techniques: Expressing, Gene Expression

    Ratio of Gd-IgA1/IgA levels in culture supernatants of tonsillar MNCs from patients with IgAN correlates with the percentage of pDCs and the expression of APRIL in tonsillar MNCs. Association between Gd-IgA1/IgA levels and tonsillar pDC frequency or gene expression in MNCs from patients with IgAN ( n = 7, red dots) and CT ( n = 8, black dots). ( A ) The ratios of Gd-IgA1/IgA in culture supernatants of tonsillar MNCs from patients with IgAN or CT. ( B ) Correlation between the Gd-IgA1/IgA ratio and the percentage of tonsillar pDCs in MNCs from patients with IgAN and CT. ( C ) Correlation between the Gd-IgA1/IgA ratio and the expression of APRIL in MNCs from patients with IgAN and CT. ( D ) Correlation between the Gd-IgA1/IgA ratio and the expression of BAFF in MNCs from patients with IgAN and CT. ( E ) Association between the APRIL and TLR9 expression levels in tonsillar MNCs from patients with IgAN and CT. Correlations were assessed using Spearman’s correlation coefficients (r) with P -values shown in each panel. ns, not significant; * P ≤ .05.

    Journal: Nephrology Dialysis Transplantation

    Article Title: Plasmacytoid dendritic cells modulate the production of mucosal IgA in IgA nephropathy

    doi: 10.1093/ndt/gfaf216

    Figure Lengend Snippet: Ratio of Gd-IgA1/IgA levels in culture supernatants of tonsillar MNCs from patients with IgAN correlates with the percentage of pDCs and the expression of APRIL in tonsillar MNCs. Association between Gd-IgA1/IgA levels and tonsillar pDC frequency or gene expression in MNCs from patients with IgAN ( n = 7, red dots) and CT ( n = 8, black dots). ( A ) The ratios of Gd-IgA1/IgA in culture supernatants of tonsillar MNCs from patients with IgAN or CT. ( B ) Correlation between the Gd-IgA1/IgA ratio and the percentage of tonsillar pDCs in MNCs from patients with IgAN and CT. ( C ) Correlation between the Gd-IgA1/IgA ratio and the expression of APRIL in MNCs from patients with IgAN and CT. ( D ) Correlation between the Gd-IgA1/IgA ratio and the expression of BAFF in MNCs from patients with IgAN and CT. ( E ) Association between the APRIL and TLR9 expression levels in tonsillar MNCs from patients with IgAN and CT. Correlations were assessed using Spearman’s correlation coefficients (r) with P -values shown in each panel. ns, not significant; * P ≤ .05.

    Article Snippet: The TLR9 agonist class C CpG-ODN (ODN 2395, InvivoGen), which stimulates pDCs and B cells [ ], was intranasally administered to each group of mice every 2 days for 3 weeks.

    Techniques: Expressing, Gene Expression